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The Seed-Feed-and-Occasionally-Weed-Way to Reverse Chronic Inflammatory, Immune, and Infectious Diseases

Majid Ali, M.D.

Bowel ecology is disrupted and its flora altered in all chronic inflammatory, immune, and infectious disorders, as well as in chronic energy deficit states, such as fibromyalgia, the chronic fatigue syndrome, and polymyalgia. I coined the phrase seed- feed-and-occasionally-weed-way to bowel-health in "The Canary and Chronic Fatigue" (1992). My purpose was to underscore the importance of addressing the issues of disrupted bowel ecology for restoring health. It is an integral part of my holistic clinical approach for caring for my patients with the above-mentioned clinical disorders. In that volume, I also explained why restoring a battered bowel ecosystem is the centerpiece of my integrative plan for reversing the chronic fatigue syndrome.

Seeding is the repopulation of the gut with microflora that have been destroyed by indiscriminate use of antibiotics or crowded out by the unrestrained proliferation of yeast and bacterial organisms such as the Proteus and Pseudomonas species. The "guardian angel bacteria" for bowel ecology belong to the Bifidobacterium and Lactobacillus species. Some other species also play protective roles. In health, these organisms provide the necessary counterbalance to the growth of yeast and pathogenic bacterial organisms. Beyond this, these organisms produce several molecules that play critical roles in our molecular defense systems.

Feeding is the use of some growth factors that the normal bowel flora require to flourish. These include biotin, pantetheine, Vitamin B12 and others. We clinicians have used Vitamin B12 for decades with good clinical results (to the great chagrin of those "academicians" who considered it quackery because they couldn't understand how this vitamin could ever help anybody except those with pernicious anemia). One of the principal mechanisms by which vitamin B12 exerts its myriad beneficial effects is by serving as a "growth hormone" for health-preserving bowel flora. Of course, this vitamin has several other essential roles. It plays a role in the citric acid cycle (the main molecular pathway for energy generation where it facilitates the conversion of methylmalonyl-CoA to succinyl-CoA) and is essential for cell maturation. Further, Vitamin B12 benefits many patients with neuropsychiatric disorders unassociated with anemia or macrocytosis (N Eng J Med 318:1720; 1988).

Occasional weeding is the use of several natural substances that are known to suppress the overgrowth of pathogenic bacteria, viruses and yeasts. During initial treatment, I frequently use oral nystatin or fluoconazole (Diflucan) for short periods of two to three weeks, partly for diagnostic and partly for therapeutic reasons (how a person with one of the ABE states responds to these agents is useful in assessing the degree of damage to bowel ecology). Extensive clinical experience has convinced me that long-term clinical results are far superior when the use of drugs is kept to a minimum.

Nystatin To Support The Seed-Feed-and-Occasionally-Weed-Way

I find judicious and intermittent use of Nystatin (an antifungal not absorbed from the gut) to be extremely valuable in controlling excessive fermentation in the colon, small intestine, stomach, esophagus, and the oral cavity.

Simple-minded efforts to "get rid of the yeast" with nystatin and "yeast-free diets" usually yield poor long-term results. Cold hands are associated with "cold bowel." Cold hands and cold bowel are the result of oxidatively-damaged thyroid enzymes (underactive thyroid gland), oxidatively-damaged autonomic nerve cells and fibers (dysautonomia) or an oxidatively- overdriven adrenalin gland (the relentless chatter of the cortical monkey). None of these problems can be effectively managed with yeast-free diets and Nystatin. Of course, there are other essential issues of nutrition, environment, food and mold allergy, and fitness. In the management of battered bowel ecosystems, it is essential to consider the biologic individuality of the patient. It is necessary to adopt an integrated, long-term approach that addresses all relevant issues of bowel flora and parasites, bowel transit time, bowel ischemic patterns, IgE- mediated disorders related to Candida and other yeast antigens, malabsorptive dysfunctions, and secondary systemic consequences.

 

Course on Bowel Health and Healing

 

* Course on Bowel Health and Healing

* Evolutionís Intelligent Design for the Alimentary Tract

* Gut Flora

Gut Immunity

* The Seed-Feed-and-Occasionally-Weed-Way

* Sick Gut Microbes Sicken Children

GERD Gastroesophageal Reflux Disorder

* Colon Ecology - Colitis by Any Name

* Colon Polyps

* Rectum

* The Butyrate Blessing

* Recipes for Healthful Aging

* Healthy Mouth, Unhealthy Mouths

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* Canker Sores

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