Insulin in excess is strongly
pro-inflammatory hormone. Indeed, pathologic
inflammation induced by hyperinsulinemia plays
central roles in weight gain, neuropathy,
nephropathy, retinopathy, and other pathologic
entities associated with pre-diabetes, gestational
diabetes, Type 2 diabetes, and insulin toxicity
caused by improper use of insulin (for example by
insulin injections taken after poor food choices).
In this tutorial, I offer some interesting
historical facts about pro-inflammatory of excess
insulin. I follow this with an illustratiice case
In 1876, W. Ebstein, a German
physician, reported that simple aspirin relieved
many of the symptoms of diabetes in some patients.
In 1901, R.T. Williamson, a British physician,
validated Ebstein's observation. His paper published
in the British Medical Journal included the
following: "sodium salicylate had a definite
influence in greatly diminishing the sugar
excretion." These early papers went unnoticed. In
1957, another paper in the British Medical
Journal reported on the case of an
insulin-dependent individual whose arthritis was
treated with high-dose aspirin regimen.
Unexpectedly, he did not require any insulin
injections during the treatment
Recently, I saw a 57-year-old
male nurse with a 21-year history of diabetes,
hypertension, coronary artery stent, early kidney
failure, and fatigue. When I told him that I wanted
to do a four-hour insulin profile test. He looked
puzzled and then said:
"My diabetologist never brought
that subject up. He keeps increasing the dose of
insulin every time my blood sugar level rises. Why
do you think doing an insulin profile test will
"I want to know how much insulin you might be
wasting." I replied.
"Why would I be wasting insulin?"
"Insulin wasting occurs when insulin receptor is
blocked, blood sugar levels continue to rise, and
the pancreas keeps producing more and more insulin."
"How is insulin receptor blocked?"
"By toxicities of foods, environment, and
"What is insulin waste?"
"Insulin wasting is a state in which the pancreas
keeps pouring insulin into the blood but the insulin
simply cannot turn the crank-shaft of insulin
receptors in the cell membranesóthe gummed cell
membranes block the insulin action, so to speak." I
He stared at me for several moments, then spoke,
"You hit the nail on the head. When I was
hospitalized for congestive heart failure and an
increasing degree of kidney failure, they were able
to control my glucose with one-fifth the insulin
dose which I was taking before ending up in the
"That was so because in the hospital your lungs
were loaded with fluids, your kidneys were shutting
down, your heart was overburdened, your tissues were
water-logged and brimming with stagnant acids and,
as a consequence of all those problems, you were
struggling with free radical storms. You're also
insulin-toxic. They gave you oxygen, cleared the
water from your lungs, supported your kidney
function, and drained the stagnant acids out of your
water-logged tissues. With those therapies, they
controlled the free radical storms in your body. As
a result of all that, they improved oxygen
utilization in your cells and saved you from insulin
toxicity," I explained.
"Makes perfect sense, doesn't it," he beamed.
"Yes, It does."
"What do we do now?"
"Now, we address all relevant issues of optimal
food choices, physical exercise, and the bowel,
blood, and liver toxicity. We will attempt to clean
up your cell membranes so that your insulin can
efficiently turn the crankshaft of insulin receptors
in those membranes. You will then need much less
insulin and will be able to avoid insulin toxicity."
I outlined our integrative program for him.