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Reversing HyperinsulinismLong-Term

Majid Ali, M.D.

No drugs are available to reverse hyperinsulinism (a state of excess insulin designated meaningfully as insulin toxicity). This leads to the common and regrettable omission on the part of doctors not to actively use integrative nondrug plans to reverse hyperinsulinism. In this article I present a case study of successful reversal of hyperinsulinism over a period of four years. First, how does hyperinsulinism develop?

The Crank-Crank-Shaft Model of Hyperinsulinism

I illustrated the beginning of hyperinsulinism (insulin toxicity) as insulin/insulin receptor dysfunction with a crank/crank-shaft analogy (for detailed information, consider my book entitled "Darwin’s drones, Oxygen, and Diabetes - Dr. Ali’s Plan for Reversing Diabetes," available at http://www.majidali.com.

Here is an important passage from that book: The cell membranes become resistant to insulin when they become chemicalizedplasticized, so to speakand hardened, immobilizing the insulin receptors embedded in the membranes. The insulin receptor is a protein that cris-crosses the cell membrane like a cord. One of the consequences of grease buildup on cell membranes is that insulin receptor becomes turned and twisted, literally and figuratively. In a previous paper, I offered the analogy of a crank and a crank-shaft to explain insulin resistance. I visualize insulin as a cranka device that transmits rotary motionand the insulin receptor protein as a crank-shaft embedded in the cell membrane.

Case Study of Hyperinsulinism Reversal

A 63-yr-old 5' 11" man weighing 211 lbs. Consulted me for hypertension, hepatitis C with cirrhosis, and hytertrophic cardiomyopathy, He had unsuccessfully received ant-viral intefreon therapy six years earlier. Table below presents his insulin and glucose profiles obtained in 2009, 2010, and 2013. Note that his peak insulin values fell from 132 in 2009 to 48.3 in 2010 to 21 in 2013. During these years, he reported incremental and sustained improvement in general health and his hepatitis viral count fell from 9.7 million to 3.6 without the use any anti-viral drugs. For professional readers, I describe the details of our integrative treatment in the 11th volume of my textbook entitled "The Principles and Practice of Integrative Medicine."

 

Insulin and Glucose Profiles of a 63-yr-old 5' 11" Man Weighing 211 lbs. With Hepatitis C and Cirrhosis, Hypertension, and Hytertrophic cardiomyopathy. His Hepatitic C Viral Count Fell from 9.7 million to 3.7 Million Copies.

9.4.2009

Fasting

1 Hr

2 Hr

3 Hr

4 Hr

Insulin (mU/dL)

15.8

57.2

132

20

11.8

Glucose

79

165

115

40

51

1.12.2010

Fasting

1 Hr

2 Hr

3 Hr

4 Hr

Insulin(mU/dL)

4

48.3

44.2

10.2

2.9

Glucose

61

148

99

50

40

10.25.2013: 30 Min Insulin, 11.6 ; Glucose, 154; Wt 201

Insulin (mU/dL)

6.4

18.4

21.0

6.0

 

Glucose

92

146

93

50

 

 

Related Articles

* Evolution’s Intelligent Insulin Design

* The Crank-Crank-Shaft Model of Insulin Resistance Insulin Toxicity

* Insulin Stress Test

* Metformin Mania

* Hypoglycemia: Diagnosis and Treatment
 

* Insulin Toxicity

* Insulin Stress Test

* Weight and Obesity
* Diabetes

* Metformin Mania

* Tutorial GG.16 The Dysox Model of Diabetes and De-Diabetization Potential. Townsend Letter-The examiner of Alternative Medicine. 2007; 286:137-145.

Tutorial GG.31 Ali M. Oxygen, Insulin Toxicity, Inflammation, And the Clinical Benefits of Chelation. Part I. Townsend Letter-The examiner of Alternative Medicine. 2009;315:105-109. October, 2009.

Tutorial GG.32 Ali M. Insulin Reduction and EDTA Chelation: Two Potent and Complementary Approaches For Preventing and Reversing Coronary Disease. Oxygen, Insulin Toxicity, Inflammation, and the Clinical Benefits of Chelation - Part II. Townsend Letter-The examiner

 

* http://www.ethicsinmedicine.us/insulin_toxicity_fatty_liver_oxygen.htm

 

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