Free Courses
Free Videos                                      Free Articles

Science, Health, and Healing Encyclopedia

 

 

 

 

 

 

 

 

 

Ali

 

 

Ali Oxygen Library
Ali Recipes

Ali SHH-Pedia

ADHD

Adrenals

Aging

Alcholism

Allergy

Anger

Anxiety Course

 

 

  Asthma

 

  Autism

 

  Autoimmune Disorders

  Autonomic System

 Bladder, Urinary

 

 BLOOD
 
 BONES

 

  BRAIN

 

 BREAST Health.diseases

Breathing for Healing

 

BONES, Joints, and Muscles

 

 

CANCER

Children's Readings

 

CardiovascularDisease

 

Cancer
Chemotherapy

Avastin
 

 

Cholesterol

Climate Chaos

Collagen Disorders

COLON

Current Topics

Cystitis

 

Dialysis

DIABETES & INSULIN Toxicity

PRE-DIABETES

 

EARS

Emotions

Energy Healing

 

Endocrine
 

 

Eyes

Estrogens

 

Ethics

Exercise

Fermentation

Foods

Gall BladderStones

Genetics

GERD

Gluten

GUT Evolution
 

Genetics

GUT

     Mouth
      Esophagus
      Stomach
      Small Intestine
      Colon
      Rectum and Anus

Healing

Healing Stories

Heart

Hepatitis

Herbs

 

History

Hormones

Immune System

 

Inflammation

Infections

INSULIN TOXICITY

Joints

Kidneys

Kitchen Matters

 

Lap Dog Journalists

Leukemia

LIVER

Lou Gehrig ALS

 

Lungs

Lyme Disease, Acute


Lyme Disease, Chronic

Lymphatic System

 

 

 

Memory

Mental Health

 

Metabolism

 

Microbiology

Minerals

Mouth

Multiple Sclerosis

 

MUSCLES

Nose

 

Nutrition

Obesity

 

Oxygen
Basic Course Advanced Course
Oxygen and Aging
Oxygen Therapeutics
Oxygen -Environment
Oxygen and 9/11
Oxygen Models of Diseases
Oxygen and Origin of Life

 

 Ovaries

Pancreas Pancreatitis

Parkinson's Disease

Philosophy of Healing

Poems Drone Democracy
Selected Poems

Polycystic Ovarian Synd

Poetry of Dr.Ali

Potassium

Progesterone

 

Rectum

Recipes

Respiratory System

 

ReproductiveSystem
 
 

SHH-Pedia

Sinusitis & Polyps

 

Skin

Sodium Salt

Spices

Spleen

Small Intestine

Stomach

 

  Stories of Soul's Sweat

 

Stress

Stroke

Throat

Thyroid

Tongue

Tonsil

 

Toxic Womb State

Pre-birth PTSD

 

Testosterone
 

 

Urinary System

 

Uterus

Video Seminars on Natural Healing

Viral Infections

Recent Videos

 
Store DVD/Books
   
  Water

War

Weight Loss

Yeast Syndromes

Zinc

 

 

 

 

The Darwin Principle for Integrated Trials

Majid Ali, M.D.

In Darwin, Dysox, and Disease (2006), I introduced the term Darwin Principle in medicine for a principle by which simple conclusions are drawn from extended and integrated study of a large body of clinical and laboratory observations. This principle accepts the validity of each clinical and scientific observation concerning any part of the whole but holds that none of them singly be accepted as the definitive evidence of any conclusion about the condition of the whole. The core tenet of the Darwin Principle is: No part can be understood except through an understanding of its relationships with the whole. I consider the Darwin Principle of crucial importance for both understanding the molecular biology of diseases, as well as for designing rational and scientifically sound treatment plans for them.

In 1831, Charles Robert Darwin (1809-1882), started his journey aboard the British Navy ship H.M.S. Beagle around South America. Over a period of five years, he accumulated an enormous number of biologic and geologic samples, studied them intensively, reflected on the interconnectedness of all of them, and formed his simple — yet comprehensive— biological theory of natural selection. In 1850, he published On the Origin of Species which, in my view, is the most significant work in biologic sciences. For individuals interested in the control of cancer, Darwin's core message is this: No aspect of cancer can be understood except through an understanding of its relationships with the whole. Translation: No treatment plans for cancer which do not address nutritional, environmental, and anger-related issues can be considered scientific.

The clinical application of the Darwin Principle calls for clinical trials which are radically different from the model of blinded and controlled trials that test single drugs at a time. The clinical trials based on the Darwin Principle must be designed to address the macro furies (toxic thoughts, toxic environment, and toxic foods), as well as the three micro furies (oxidosis, acidosis, and dysoxgenosis) of disease. Such investigations can be conducted only as open, integrated trials in which teams of experienced clinicians enter a sizeable number of individuals with well-defined clinicopathologic entities into trials and then are free to address all macro and micro issues on basis of the needs of individual patients. The trial outcome is determined by evaluation of the results by patients as well as clinicians employing objective and subjective criteria. The integrity of an outcome is assured by ensuring that: (1) a sufficiently large number of clinicians participate in the trial who categorically have no financial interest in the outcome; (2) all trials test—then validate or refute—integrative management plans for all patients treated at the center at which those trials are conducted; and (3) all integrative trials are carried out for sufficiently extended periods of study so that the conclusions drawn from the data truly represent long-term results of the trial. In Darwin, Dysox, and Disease (2006), I present a compendium of my philosophic discussion of the Darwin Principle and the results of several long-term clinical outcome studies designed and conducted following the Darwin Principle.

The matter of patients deciding the efficacy of treatment is likely to raise some eyebrows. We have raised generations of doctors who think no clinical trials must be considered valid in which the patients have had anything to say in determining the outcome of the trial. However, who can gauge the quality of sleep or energy — may I ask—better than the patient himself? Or the freedom from toxic thoughts? Or the qualities of mood, memory, and mentation? Or digestive and menstrual health? Or sexual drive? Or absence or presence of dry skin and muscle suppleness? For decades, I have been baffled by hearing otherwise intelligent doctors mindlessly insist that the patient's voice must be vigorously excluded from clinical trials.

 

Welcome  

Who Is Dr. Ali?

Dr. Ali's Full CV

Peer Reviews of Dr. Ali' Work

 

Dr. Ali's Philosophy

 
 

 

VIDEO Courses

Philosophy of Integrative medicine 

Dr. Ali's Recent Videos

Click here to order Prof. Ali's Video Courses, digital aand print books, DVD seminars, and lectures on CD sets.

 

Now Available as
Instant Download

Integrative Protocols -
Vol 12 Principles and Practices
of Integrative Medicine

Includes
Dr. Ali's
IV and IM formulations

E-Book 12



Integrative Protocols -
Vol 11 Principles and Practices
of Integrative Medicine
E-Book 11


Dr. Ali discusses Dysoxygenosis and varying chronic diseases.

NEW BOOK!

Book Diabetes

OR
Instant Download