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Alzheimer’s, Oxygen, and Tau Protein

Majid Ali, M.D.

In the companion article entitled The Oxygen Model of Alzheimer's Disease," I explain that Alzheimer's disease is caused by dysfunctional oxygen metabolism in the brain resulting from toxicities of foods, environments, and thoughts. In 1994, I proposed the oxidative model of Alzheimer's disease in my book RDA Rats, Drugs and Assumptions.  Some years later I expanded that model to focus on oxygen homeostasis and designated it as The Oxygen Model Alzheimer's Disease.  I provided the scientific basis of this model in my book Oxygen and Aging (2000). This is a unifying model that: (1) integrates all verifiable aspects of the prevailing models of the disease; and (2) offers a rational and scientifically sound integrative management plan. The core tenet of the model is that all relevant oxygen-related issues must be addressed to maximize the potential benefits.

On February 1, 2012, The New York Times published an article entitled "Path Is Found for the Spread of Alzheimer’s." The writer, Mr. Gina Kolata, reported that "Alzheimer’s disease seems to spread like an infection from brain cell to brain cell, two new studies in mice have found. But instead of viruses or bacteria, what is being spread is a distorted protein known as tau." Based on that, Mr. Kolata made a remarkable claim of a breakthrough.

An Antibody Cure?

Consider his wild enthusiasm in the following sentence: "The new studies provide an answer. And they indicate it may be possible to bring Alzheimer’s disease to an abrupt halt early on by preventing cell-to-cell transmission, perhaps with an antibody that blocks tau." It is safe to predict that an antibody drug, when developed on this promise, will at best offer minimal and temporary benefits. My reason is that the tau protein abnormalities develop as a consequence of toxicities of foods, environment, and thoughts. No antibody drug can address these problems.

Cellular and Molecular Environments Do Not Matter

Gina Kolata ends his article with the following astonishing sentence: "It isn’t a bad neighborhood. It is contagion from one neuron to another." Translation: toxicities of nutrition, environment, and thoughts do not matter in the cause of Alzheimer’s disease.

Mr. Kolata is well known for making wild and irresponsible statements about curing diseases. Consider a quote from his front page story in The New York Times of May 3, 1998: "Judah is going to cure cancer in 2 years...Dr. Watson said that Dr. Folkman [a cancer researcher at Harvard University] would be remembered along with scientists like Darwin as someone who permanently altered civilization."

For readers interested  in my Oxygen Model of Cancer, I suggest my book "The Crab, Oxygen, and Cancer - The Dysox Model of Cancer (2007).

The New York Times report need not comfort anyone. In 1958, in medical school I was taught Alzheimer's disease is caused by a protein called beta amyloid which is deposited around the brain cells (see illustration below). About thirty years later, the focus shifted to deposition of tau protein within the neurons. Now in 2012, Mr. Kolata still cannot see that the deposits of amyloid an tau proteins do not descend from Mount Olympus. Rather, they are caused by energetic-molecular insults inflicted by toxicities of foods, environments, and thoughts as recognized in The Oxygen Model of Alzheimer's Disease.

Tau Protein Inside (L), Amyloid Protein Outside (R)

 

 

 

 

Related Articles

Related Articles

k Memory Loss - Classification of Disorders

k Anatomy of the Parasympathetic Nervous System

k   Memory Lapses Due to Adrefog

k   The Oxygen Model Alzheimer's Disease

k  Alzheimer’s, Oxygen, and Tau Protein

k  Memory Loss - Classification of Disorders

k  Being Your Own Memory Doctor

k  Hanging From Trees for Memory Loss

k  Memory Lapses Due to Anoxifog and Neuroxifog

k  Anatomy of the Parasympathetic Nervous System

k  Rising Prevalence of Autism Spectrum

k  Brain Edema

k Cerebral Ischemia and Infarction

k  Brain Aneurysms

k  Multiple Sclerosis (MS) and Demyelinating Diseases

k  Parkinson’s Disease

k  Pick's Disease

k Alzheimer’s, Oxygen, and Tau Protein

 

 

 Memory Lapses Due to Adrefog

The Oxygen Model Alzheimer's Disease

* Alzheimer’s, Oxygen, and Tau Protein

* Memory Loss - Classification of Disorders

* Being Your Own Memory Doctor

* Hanging From Trees for Memory Loss

* Memory Lapses Due to Anoxifog and Neuroxifog

* Anatomy of the Parasympathetic Nervous System

*Rising Prevalence of Autism Spectrum

* Brain Edema

* Cerebral Ischemia and Infarction

Brain Aneurysms

*  Multiple Sclerosis (MS) and Demyelinating Diseases

Parkinson’s Disease

Pick's Disease

The Oxygen Model Alzheimer's Disease

* Anatomy of the Parasympathetic Nervous System

* Alzheimer’s, Oxygen, and Tau Protein

 

 

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